The guys bought the car last June last year and it took them six months to get it into shape and fit it out, Czech website České noviny reports on Wednesday.
"We have not done anything particularly special to it, only installed a protective cover on the bottom of the engine and put a car trunk on top," it quotes Filip Vogel as saying.
Vogel, who is completing his doctoral studies at the Faculty of Civil Engineering of Czech Technical University in Prague, had previously driven through Europe, South Africa, South America and some of the Hawaiian Islands.
The two residents of the town of Čestice in the South Bohemian Region of the Czech Republic are planning a to take the Pamir Highway, the Silk Road from Tajikistan to Kyrgyzstan and the so-called death road in the Bolivian Andes.
They plan to regularly post reports of their journey on the internet and expect to get back home by March 2018 at the latest.