"We have asked the Saudi government to investigate all credible reports of civilian casualties resulting from coalition-led airstrikes and, if confirmed, to address the factors that led to them," the official said on Wednesday.
Earlier in the week, at least 27 people, mainly women and children, were killed in two separate airstrikes by the coalition against opposition Houthi forces in Yemen.
"Civilians deaths in any conflict are tragic. We take all accounts of civilian deaths due to the ongoing hostilities in Yemen very seriously," the official stated. "We urge all sides to exercise restraint, comply with international humanitarian law, and take all feasible measures to minimize harm to civilians."
The official said that a solution to the Yemeni conflict must be a political one, and called on all sides to the conflict to urgently return to the negotiation table.
On Tuesday, The UN special advisers criticized the international community for being silent about the threat to civilians in the increased number of air attacks in Yemen.
The country has been engulfed in a military conflict between the opposition Houthis and government forces.
In late March, the Saudi-led coalition of nine Arab states began an aerial campaign against Houthi positions at the request of the country's president-in-exile Abd Rabbuh Mansur Hadi.
According to United Nations estimates, at least 2,204 civilians have been killed in the conflict in Yemen.