"The participation of such terrorist groups as PYD make the talks on Syria fruitless. It is very dangerous," Cavusoglu said at a press conference in Ankara.
Cavugoslu accused "other countries" of "attempting to blur" the list of opposition delegates in talks with Syrian government representatives that were postponed after initially being scheduled for Monday in Geneva.
He backed the "soonest" start of intra-Syrian talks and said a political settlement of the nearly five-year internal conflict in the Arab republic was the "only solution."
Turkish President Recep Tayyip Erdogan and Prime Minister Ahmet Davutoglu reiterated over the weekend that Turkey makes "no distinction" between the PKK and the PYD.
Cavusoglu added al-Nusra Front and the Daesh jihadist group, banned in many countries including Russia, to the list of terrorist groups Ankara equates to the PKK and the PYD.