On Tuesday, the Washington Post reported that the FDA would consider stricter guidelines to approve a vaccine in order to improve transparency and public trust.
"That has to be approved by the White House, we may or may not approve it," Trump said on Wednesday. "That sounds like a political move."
Many Democrats have accused Trump of trying to fast-track the vaccine approval process in order to get one delivered ahead of the November reelection. Democratic presidential nominee Joe Biden has recently urged the regulator agency to maintain transparency and independence.
Trump has promised that 100 million doses of a vaccine will be distributed throughout the United States by the end of the year. He said a vaccine could be available for distribution before the presidential election on 3 November.
The United States has registered nearly 7 million cases of COVID-19 and more than 201,000 deaths caused by the disease as of Wednesday evening, according to the Johns Hopkins University count.