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Don’t Fear the Crazy, the Mini Brains Are on the Way!

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They may only be the size of a few cells but a composition of organic matter that mimics the brain has been discovered by scientists and is thought to potentially help diagnose and treat disease.

At the annual American Association for the Advancement of Science meeting in Washington, scientists announced the development of small, cellular globules that act like human brains, complete with electrical pulses that occur in the natural functioning of a brain.

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The globules are thought to be likely to help researchers in the near future study common illnesses and disorders, including autism, Parkinson’s disease, multiple sclerosis, or Alzheimer’s. Researchers suggest the discovery could also lead to cures for stroke, brain trauma and infections. 

Thomas Hartung of Johns Hopkins University Bloomberg School of Public Health led the team that developed the “mini brains.” Hartung hopes to have commercially viable examples available by the end of the year.

There are countless possibilities of how these “brains” could help research including its use by pharmaceutical companies when testing new drugs, to provide a more realistic model, making it unnecessary to test on animals. 

“This is opening up for a more human-relevant research to study diseases and test substances,” Hartung says. "Nobody should have an excuse to still use the old animal models."

Hartung said the study of autism and Downs Syndrome are particularly promising, however admitting there isn’t enough evidence yet to make anything more than promises.

“I’m selling hopes,” he told Ars Technica.

Other scientists not connected to the research have said that there are many ways in which the development could benefit medical research and help discover how the brain works, even potentially eliminating maladies of the mind and some forms of insanity.

Perhaps the future holds the promise of retaining one’s marbles, even in the face of dire experience.

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