South Wales Police say they are responding to a "serious incident" which took place in Treorchy at midday on Friday.
No further details about the incident have emerged as yet, but it is said to involve "a number of casualties".
"The street has been closed off and people are advised to avoid the area until further notice. Updates will be released when they are available", SWP said on Twitter.
The officers asked the public to "refrain from posting speculation about the incident".
"We will release further information when appropriate to do - your support is appreciated", the police added.
#INCIDENT | Police units are currently dealing with a serious incident which occurred in Baglan Street, Treorchy, @swpRCT, at approximately midday today.— South Wales Police (@swpolice) March 5, 2021
Ambulance crews are also in attendance as the incident involves a number of casualties.
SWP are also seeking witnesses but the nature of the incident has not been disclosed.
The Sun newspaper has described the incident in the village as a "stabbing attack" citing police accounts, but SWP has not officially confirmed this.
The paper claims that one man is feared dead and a number of others seriously injured after a stabbing attack in a local Blue Sky Chinese takeaway.
Labour MP for Rhondda Chris Bryant described the situation as "disturbing events" but also did not give any further details into the incident.
Residents say they have seen police cars, first responders and ambulances, including an air ambulance, milling about the area, but were not told what was going on.
Some locals have reportedly described the scene of the incident as a "bloodbath".
So there's currently some sort of major incident happening in Ynyswen, just down the road from my house— Joe Glass la!🏳️🌈Order Pride Omnibus FEB210312 (@JosephGlass) March 5, 2021
We got ambulances, cop cars, first responders and an air ambulance so far #Treorchy
The Welsh Ambulance Service say they have attended the scene of the incident with "one rapid response vehicle, three emergency ambulances, our hazardous area response team and the Wales Air Ambulance" after being called to the area at 12:00 GMT.
Emergency services are responding to a "serious incident" in a south Wales village where "multiple casualties" are being treated for injuries.— LBC News (@LBCNews) March 5, 2021
The nature of the incident, which happened in Treorchy at around midday, is not yet clear.
Read more here: https://t.co/Q4k1EAhBt4 pic.twitter.com/8BhDFTdzEj
Users on social media were trying to serach for answers of what could have happened at the scene as police still did not give any further details into the incident.
Unclear right now but sounds like something bad has happened in Ynyswen, near Treorchy, hope everyone there is OK :(— Reece Hughes 🐝 (@TheMadMidlander) March 5, 2021
Treorchy, South Wales: Police dealing with ‘serious incident’ involving ‘a number of casualties’ right now 😳— LTH🇬🇧london (@LTHlondon) March 5, 2021
Any word on what this incident is, anybody?