Scientists from Vernadsky Crimean Federal University, together with their colleagues from the and Forestry Mechanization, have developed and synthesized a new plant protection compound based on the DNA of the gypsy moth. According to the developers, the new DNA insecticide only affects larvae and then quickly self-destructs without damaging the environment. The research was published in Scientific Reports.
"We have proposed a novel biotechnology to protect plants from insect pests using DNA insecticide with improved insecticidal activity based on the gene sequence of the gypsy moth (Lymantria dispar). Compared with existing insecticides, the oligoRIBO-11 insecticide is more affordable and faster acting. It also causes a higher mortality among both L. dispar larvae grown in the lab and those collected from the forest," said one of the authors, senior lecturer Volodymyr Oberemok.
Creating the biotechnology to protect plants from the gypsy moth led to the next stage, the development of DNA-based insecticides based on a new antisense oligoRIBO-11 sequence from the 5.8S ribosomal RNA gene.
"Our research has proven the effectiveness of the new technology, which makes the oligoRIBO-11-based insecticide a potential candidate for the development of an environmentally friendly product to be used in forestry," said Volodymyr Oberemok.
Various methods are used to fight the gypsy moth, such as clearing eggs from trees, setting traps for mature larvae, and using chemical and biological products. Over the last decade, Crimean University researchers have been investigating the possible use of DNA insecticides synthesized using the moth's own DNA to destroy the pest in the caterpillar stage.