"The cargo spacecraft's remaining fragments fell into the Pacific Ocean after re-entry into the Earth's atmosphere is 11:19 a.m. Moscow time [81:49 GMT]," Mission Control said.
The Progress M-01M cargo spacecraft undocked on Friday from the International Space Station and served as a temporary space lab before its "burial" in the Pacific Ocean.
The craft was launched from the Baikonur space center in Kazakhstan on November 26 and docked with the world's only orbital station four days later.
The Progress delivered 2.5 tons of cargo to the orbital station, including food and water supplies for the current crew, as well as fuel and scientific equipment.
The spacecraft was also used on December 17 for a trial adjustment of the ISS's orbit.
Preparations are currently under way in Baikonur for the launch of a Soyuz-U carrier rocket bearing a cargo spacecraft, Progress M-66. Takeoff is scheduled for February 10.
The cargo ship is scheduled to dock with the ISS three days after liftoff to deliver fuel, food, water and equipment.