"Even if there is somebody, who wants to radically change the US foreign policy, cooperation [with US] will bring a lot more benefits to us. There will not be many changes in the Greek-US relations over the next period," Tsipras said at a joint press conference with US outgoing President Barack Obama.
Obama, who is set to leave the Oval office in January, is in Greece as part of his final foreign trip, which also includes stops in Germany and Peru.
Republican Trump secured a victory in the US presidential election on November 8 with 290 electoral votes against his Democratic rival Hillary Clinton's 232. Trump's inauguration will be held on January 20, 2017.