"The Secretary [Kerry] has just spoken or is speaking with [Russian Foreign] Minister Lavrov," the official said.
Earlier on Friday, Russian and Syrian militaries announced that a "regime of silence" would come into being in the western Latakia province and Damascus suburbs on April 30 at midnight.
The regime of silence agreement is expected to last for 72 hours in Latakia and 24 hours in Damascus.
The State Department senior official noted that the conversation between the two leaders is a regular occurrence.
The regime of silence was negotiated and will be enforced by Russia and the United States only days after UN Special Envoy for Syria, Staffan de Mistura, acknowledged that the ceasefire was barely alive, and urged the two powers to save the Syrian peace process.