"The remarks were a big insult to Afghanistan people and are strongly condemned," Karzai said as quoted in a statement.
The former president has also expressed concern over US-Pakistani discussions on peace in Afghanistan.
On Monday, Trump said during his meeting with Pakistani Prime Minister Imran Khan that he could wipe Afghanistan off the face of the earth in 10 days but decided not to do so as it would cause 10 million deaths. The statement caused outrage in Afghanistan with country's President Ashraf Ghani demanding clarification.
The scandal broke as US Special Representative for Afghanistan Zalmay Khalilzad arrived in Kabul on Tuesday. The envoy's visit is aimed at facilitating the Afghan peace process. During his visit, Khalilzad will discuss with Kabul the formation of a national negotiating team that can participate in intra-Afghan negotiations. The diplomat will then travel to Qatar's capital Doha to hold talks with the Taliban movement.
Afghanistan is suffering from an unstable political, social and security situation due to the activity of the Taliban movement and Daesh* terrorist group. Pakistan shares a border with Kandahar, one of Afghanistan's most turbulent provinces that is densely populated with Taliban militants.
*Daesh [ISIL, the Islamic State, ISIS] - a terrorist group banned in Russia and many other countries