According to Hamas spokesman Ismail Radwan, Trump's "decision will open the gates of hell on US interests in the region."
The political and militant group issued its statement on Wednesday, immediately following Trump's announcement that Washington would be relocating the US Embassy from Tel Aviv to Jerusalem in six months' time.
"Trump's decision on Jerusalem will not succeed in changing the fact that Jerusalem is an Arab Muslim land," Radwan said, according to AFP.
On the eve of Trump's announcement, the Israeli Defense Forces started preparing for unrest in the West Bank, East Jerusalem and the Gaza Strip, the latter controlled by Hamas, after the millitant group announced plans to hold a "day of rage" if Washington went ahead with the decision.
Radwan stated that the US president's decision was "foolish," and that "time will prove that the biggest losers [from it] are" Trump and Israeli Prime Minister Benjamin Netanyahu.
On Wednesday, Trump announced that it was "time to officially recognize Jerusalem as the capital of Israel," and ordered the State Department to prepare to move the US Embassy. He added that he would do "everything" in his power to faciliate Israeli-Palestinian reconciliation.