"We do not use any ammunition prohibited by the UN. You can rest assured," Lavrov said in an interview with the BBC broadcaster.
The diplomat said "compelling evidence" should be presented before accusing Moscow of attacking the civilian population in Syria.
Russia is taking all necessary measures to avoid civilian hardship in Syria amid an ongoing military campaign there, Sergey Lavrov said.
"We are taking all the necessary precautions to avoid civilian casualties. Collateral damage was caused not by us, but you know who. At the same time, as I said we are doing everything possible to avoid civilian casualties in any scenario. If that happens, we are very sorry about this, but each charge should be thoroughly investigated," Lavrov said in an interview with the BBC World.