"We in Scotland are fed up of persecution by the SNP leader who is solely intent on getting independence at any cost. As a result, Scotland is suffering hugely," the petition, launched on the UK government’s official website, reads.
The UK parliament must consider all petitions which reach more than 100,000 signatures for debate.
On Wednesday, a survey by ScotCen's Scottish Social Attitudes found that 46 percent of the Scottish public support independence, with 62 percent supporting the country remaining in the European Union.
The Scottish parliament will reportedly decide as early as next week whether Sturgeon should be given authority to ask the UK parliament for the power to hold a second referendum.
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