The plane has crashed during landing approach due to bad weather conditions, the ministry noted.
"A cargo plane of Turkish airlines en route from Hong Kong crashed while landing in Manas airport in Kyrgyz capital due to poor weather conditions," head of Crisis Management Center's told RIA Novosti.
The plane has crashed in a village, destroying at least 15 homes.
According to Kyrgyz government, the catastrophe took lives of at least 20 people, including 6 children.
"According to the preliminary data, 15 houses are ruined, 20 people from them died," a representative of Kyrgyz Emergency Ministry told RIA Novosti.
Kyrgyz Emergency Ministry also reported that there were 4 crew members onboard aircraft, one of them survived.