According to the statement, the Nusra Front has been shelling the Syrian army positions from the Narb-Nafsa settlement.
"In order to stabilize the situation, the Russian Aerospace Forces carried out missile and bomb attacks against the attacking units of the Nusra Front militants in regions north of Aleppo and attack positions of terrorists near the Narb-Nafsa settlement," the statement reads.
The center reiterated that no attacks were being carried out against the opposition groups in Syria which had agreed to the ceasefire.
Russia and the United States reached an agreement on the ceasefire in Syria on February 22. The ceasefire took effect at midnight on Saturday Damascus time.
The UN Security Council unanimously adopted Resolution 2268 endorsing the Russia-US agreement on the cessation of hostilities in Syria on February 26, shortly before the ceasefire came into force.
Islamic State and the al-Qaeda affiliated Nusra Front, outlawed in many countries including Russia, are designated as terrorist by the UN and are not affected by the Syria truce.