"I am confident that we’ll find an agreement this week," Moscovici told France Inter radio a day after a European extraordinary summit on the Greek debt issue.
According to the commissioner, there is still work to be done on tax and pension reform.
"The aim is more growth and jobs with structural reforms," Moscovici said.
Athens is trying to unlock a new bailout deal in exchange for reforms. The current deal expires on June 30.
On Monday, key EU leaders and international creditors met with Greek Prime Minister Alexis Tsipras in Brussels to discuss his latest reforms proposal, which European Council President Donald Tusk deemed a major step toward settling the current situation.