Expedition 17 comprises Commander Sergei Volkov and Flight Engineer Oleg Kononenko, who will spend six months on board the orbital station, while Yi So-yeon, a biotechnology engineer, will be in orbit for only ten days.
During their stay on the ISS, the new crew will monitor docking with several space shuttles and cargo craft, move the Soyuz TMA-12 from the Zarya module to the Zvezda module on the Russian segment of the orbital station, and conduct at least one spacewalk.
Their scientific research program will consist of over 45 experiments, including studies into the growth of proteins and polymers, forecasting earthquakes, and the influence of space on various life forms, including human beings.
Last week, Europe's first space freighter, Jules Verne, delivered over 7.5 metric tons of supplies to support the operation on the orbital station for another six months.
Members of the current 16th expedition, Commander Peggy Whitson and Flight Engineer Yuri Malenchenko, will return to Earth with So-yeon Yi in the Soyuz TMA-11 spacecraft on April 19, while Flight Engineer Garrett Reisman will join Expedition 17.