The arrest comes at a time of strained relations between Caracas and Washington. In recent weeks, Maduro has repeatedly accused the United States of plotting to overthrow him.
"We have captured some US citizens in undercover activities, espionage, trying to win over people in towns along the Venezuelan coast," Maduro said. Venezuelan president did not specify how many people were detained or when the arrest took place.
The US pilot was arrested in the border state of Tachira. Maduro did not disclose his identity, only saying that he was of Latin origin and carried "all kinds of documentation." Venezuelan authorities are reportedly interrogating him.
Earlier, Maduro said that several prominent US politicians, including former US President George W. Bush and former US Vice President Dick Cheney, were banned from entering the country, labeling them "terrorists" for US involvement in Syria, Iraq and Vietnam.
Maduro also announced Venezuela would start limiting the number of diplomatic staff the US can have in the country.
